Difference between revisions of "MassSpec research"

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This will hold the stuff for my mass spec research with Carl Ebeling as my advisor.
 
This will hold the stuff for my mass spec research with Carl Ebeling as my advisor.
  
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'''2/15/06'''
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So now its downloading XTandem, figuring out what's going on there and waiting for some example data from John. Though I should have plenty to do in figuring out XTandem without the data . .. .
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Meeting with Carl and John 2:00 on Friday. Don't forget.
  
 
==Papers from John Keane==
 
==Papers from John Keane==
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to how it works:
 
to how it works:
  
[http://www.proteome.ca/x-bang/tandem/docs/scoring-state-final.htm X! Tandem flow chart]
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[http://www.proteome.ca/x-bang/tandem/docs/scoring-state-final.htm X! Tandem flow chart (Not yet useful)]
Craig R, Cortens JP, Beavis RC.
 
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15595733&query_hl=7&itool=pubmed_docsum>
 
Related Articles,
 
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Display&dopt=pubmed_pubmed&from_uid=15595733>
 
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15595733&itool=iconabstr&query_hl=7&itool=pubmed_docsum>
 
Open source system for analyzing, validating, and storing protein identification data. J Proteome Res. 2004 Nov-Dec;3(6):1234-42.
 
Craig R, Beavis RC.
 
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14976030&query_hl=7&itool=pubmed_docsum>
 
Related Articles,
 
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Display&dopt=pubmed_pubmed&from_uid=14976030>
 
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14976030&itool=iconfft&query_hl=7&itool=pubmed_docsum>
 
TANDEM: matching proteins with tandem mass spectra.
 
Bioinformatics. 2004 Jun 12;20(9):1466-7. Epub 2004 Feb 19.
 
  
http: //www.eecg.toronto.edu/~jayar/pubs/alex/RCM_HAPI_.pdf
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15595733&query_hl=7&itool=pubmed_docsum Open source system for analyzing, validating, and storing protein identification data. (Useful soon I think)]
http: //falsepositives.blogspot.com/2005/03/mass-spectrometry-analysis-with-field.html
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Display&dopt=pubmed_pubmed&from_uid=15595733 Related papers.]
  
Research Article
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14976030&query_hl=7&itool=pubmed_docsum TANDEM: matching proteins with tandem mass spectra. (Not yet useful)]
Hardware-accelerated protein identification for mass spectrometry
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Display&dopt=pubmed_pubmed&from_uid=14976030 Related papers.]
Anish T. Alex 1 2, Michel Dumontier 2, Jonathan S. Rose 1, Christopher
 
W. V. Hogue 2 *
 
1Department of Electrical and Computer Engineering, University of
 
Toronto, 10 King's College Road, Toronto, Ontario, M5S 3G4 Canada
 
2Blueprint Initiative, Samuel Lunenfeld Research Institute, Mount Sinai
 
Hospital, 522 University Avenue, Suite 900, Toronto, Ontario, M5G 1W7
 
Canada
 
email: Christopher W. V. Hogue (chogue@blueprint.org)
 
  
*Correspondence to Christopher W. V. Hogue, Blueprint Initiative, Samuel
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[http://www.eecg.toronto.edu/~jayar/pubs/alex/RCM_HAPI_.pdf Hardware-accelerated protein identification for mass spectrometry (Useful)]
Lunenfeld Research Institute, Mount Sinai Hospital, 522 University
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Avenue, Suite 900, Toronto, Ontario, M5G 1W7 Canada.
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[http://falsepositives.blogspot.com/2005/03/mass-spectrometry-analysis-with-field.html Short analysis of the Toronto work on some blog (Not useful yet)]
  
  
  
 
==Other pages==  
 
==Other pages==  
http://pubs.acs.org/cgi-bin/abstract.cgi/ancham/2003/75/i04/abs/ac0258709.html
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[http://www.thegpm.org/ The Global Proteome Machine Organization (Tons of open-source code to validate designs and such)]
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[http://pubs.acs.org/cgi-bin/abstract.cgi/ancham/2003/75/i04/abs/ac0258709.html A Method for Assessing the Statistical Significance of Mass Spectrometry-Based Protein Identifications Using General Scoring Schemes (Sounds useful)]
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[http://www.thegpm.org/GPM/references.html Literature References for The GPM Project (literary references are always good)]
  
http://www.thegpm.org/GPM/references.html
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14512343&query_hl=6&itool=pubmed_docsum Designing hardware for protein sequence analysis (sounds related)]

Latest revision as of 04:43, 16 February 2006

This will hold the stuff for my mass spec research with Carl Ebeling as my advisor.

2/15/06

So now its downloading XTandem, figuring out what's going on there and waiting for some example data from John. Though I should have plenty to do in figuring out XTandem without the data . .. .


Meeting with Carl and John 2:00 on Friday. Don't forget.

Papers from John Keane

he safest and quickest route to get started is probably to accelerate the "search" process (like the Toronto team did), based on the popular open-source algorithm in the "X!Tandem" program. Here are a few links to how it works:

X! Tandem flow chart (Not yet useful)

Open source system for analyzing, validating, and storing protein identification data. (Useful soon I think) Related papers.

TANDEM: matching proteins with tandem mass spectra. (Not yet useful) Related papers.

Hardware-accelerated protein identification for mass spectrometry (Useful)

Short analysis of the Toronto work on some blog (Not useful yet)


Other pages

The Global Proteome Machine Organization (Tons of open-source code to validate designs and such)

A Method for Assessing the Statistical Significance of Mass Spectrometry-Based Protein Identifications Using General Scoring Schemes (Sounds useful)

Literature References for The GPM Project (literary references are always good)

Designing hardware for protein sequence analysis (sounds related)